Ankylosing spondylitis is a form of which arthritis?

Ankylosing spondylitis is a form of which arthritis?

• A. Osteoarthritis
• B. Rheumatoid arthritis
• C. Gout
• D. Psoriatic arthritis

Answer: (B)

Ankylosing spondylitis is an inflammatory arthritis that principally targets the spine and sacroiliac joints and belongs to the seronegative spondyloarthropathies. This means it commonly tests negative for rheumatoid factor and is driven by axial inflammation with features like back pain that improves with exercise and HLA-B27 association. Rheumatoid arthritis, by contrast, is an autoimmune inflammatory arthritis that typically affects peripheral joints (especially small joints of the hands and feet) and is often RF or anti-CCP positive, with a different pattern of joint involvement and systemic features. Osteoarthritis is degenerative, involving a breakdown of joint cartilage rather than an inflammatory process; gout is caused by uric acid crystal deposition; psoriatic arthritis is another seronegative inflammatory arthritis that can affect the spine but Ankylosing spondylitis is classified as a distinct axial spondyloarthropathy.

Ankylosing spondylitis is an inflammatory arthritis that principally targets the spine and sacroiliac joints and belongs to the seronegative spondyloarthropathies. This means it commonly tests negative for rheumatoid factor and is driven by axial inflammation with features like back pain that improves with exercise and HLA-B27 association. Rheumatoid arthritis, by contrast, is an autoimmune inflammatory arthritis that typically affects peripheral joints (especially small joints of the hands and feet) and is often RF or anti-CCP positive, with a different pattern of joint involvement and systemic features. Osteoarthritis is degenerative, involving a breakdown of joint cartilage rather than an inflammatory process; gout is caused by uric acid crystal deposition; psoriatic arthritis is another seronegative inflammatory arthritis that can affect the spine but Ankylosing spondylitis is classified as a distinct axial spondyloarthropathy.