Which CPT code corresponds to colonoscopy with biopsy?

Which CPT code corresponds to colonoscopy with biopsy?

• A. 45385
• B. 45380
• C. 45378
• D. 45386

Answer: (B)

Taking a tissue sample during a colonoscopy is billed as a colonoscopy with biopsy. The CPT code that represents this combination is 45380, which denotes a flexible colonoscopy performed with biopsy. The other codes in the list are used for colonoscopy procedures that involve other actions (such as removal of polyps or other therapeutic interventions) or for cases without biopsy, so they don’t match the scenario of colonoscopy with biopsy alone. If biopsies are taken and polyps are removed in the same procedure, you would report the biopsy code plus the appropriate polypectomy code.

Taking a tissue sample during a colonoscopy is billed as a colonoscopy with biopsy. The CPT code that represents this combination is 45380, which denotes a flexible colonoscopy performed with biopsy. The other codes in the list are used for colonoscopy procedures that involve other actions (such as removal of polyps or other therapeutic interventions) or for cases without biopsy, so they don’t match the scenario of colonoscopy with biopsy alone. If biopsies are taken and polyps are removed in the same procedure, you would report the biopsy code plus the appropriate polypectomy code.